Pacific Biosciences of California Inc (PACB) Q3 2024 Earnings Call Highlights: Navigating Growth and Challenges with New Product Launches

Despite revenue fluctuations, Pacific Biosciences of California Inc (PACB) focuses on innovation and strategic partnerships to drive future growth.

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Summary
  • Total Revenue: $40 million, up 11% from the second quarter of 2024.
  • Instrument Revenue: $16.8 million, a decrease of 52% from the third quarter of 2023.
  • Consumables Revenue: $18.5 million, increased 10% year over year.
  • Service and Other Revenue: $4.7 million, compared to $4.1 million in the third quarter of 2023.
  • Nongaap Gross Margin: 33%, compared to 32% in the third quarter of last year.
  • Nongaap Operating Expenses: $62.4 million, a 31% decrease from the third quarter of 2023.
  • Nongaap Net Loss: $46.0 million, representing 17¢ per share.
  • Cash and Investments: $471 million at the end of the third quarter.
  • Revo System Shipments: 22 systems delivered to 22 different customers.
  • Annualized Pull Through on Revo Platform: Approximately $255,000.
  • Headcount: 575 employees at the end of the quarter.
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Release Date: November 07, 2024

For the complete transcript of the earnings call, please refer to the full earnings call transcript.

Positive Points

  • Pacific Biosciences of California Inc (PACB, Financial) unveiled several new products, including the Vega benchtop sequencer, which is expected to make long-read sequencing more accessible.
  • The company reported a sequential increase in total revenue by 11% from the second quarter of 2024, indicating a return to growth.
  • Consumable revenue grew by 10% year over year, showing strong demand for PACB's products.
  • The company has made significant progress in reducing production costs and operating expenses, aiming to be cash flow positive by the end of 2026.
  • PACB's strategic partnerships and collaborations, such as with the National Institute of Health of Korea and Singapore's National Precision Medicine Program, are expanding its market reach and application of its technologies.

Negative Points

  • Despite the sequential revenue growth, total revenue was down compared to the third quarter of 2023, indicating challenges in maintaining year-over-year growth.
  • The company continues to face a difficult macroeconomic environment, with prolonged sales cycles and constrained customer capital expenditure budgets.
  • Fourth-quarter revenue is expected to be flat to slightly up compared to the third quarter of 2024, suggesting limited short-term growth.
  • There is potential for cannibalization between the new Vega platform and existing products, which could impact sales dynamics.
  • The company experienced delays in closing some sales, particularly in Europe, due to tender processes being postponed.

Q & A Highlights

Q: What has been the feedback from customers on the cost tradeoff of the new Spark chemistry, and how does the reduced DNA input requirement impact potential demand?
A: Christian Henry, President and CEO, stated that the feedback on Spark has been remarkable, with the $500 list price catalyzing more projects. The reduced DNA input requirement of 500 nanograms unlocks significant new demand, potentially millions of samples, as it allows more sample types to be sequenced with HiFi technology.

Q: How does the Vega launch impact the demand for long-read sequencing in smaller labs versus larger service providers?
A: Christian Henry explained that Vega will likely open up more demand for service providers over time, as more people get their hands on HiFi sequencing. While there may be initial tension, Vega's lower price point could pressure service providers to reduce prices, ultimately increasing demand for sequencing services.

Q: Can you discuss the potential overlap and cannibalization between Vega and Revo platforms?
A: Christian Henry noted that there is little overlap between Vega and Revo, as they serve different throughput needs. Vega is seen as a walk-up instrument for smaller projects, while Revo is suited for larger scale projects. The launch of both platforms is part of a strategy to offer a range of sequencing solutions without significant cannibalization.

Q: Why was the decision made to reduce the Revo list price to $599,000, and how does it relate to the Vega launch?
A: Christian Henry stated that the price reduction reflects productivity improvements and aligns the list price with actual ASPs. This change aims to drive more demand by making the technology more accessible, without significantly impacting realized revenue.

Q: How does the company plan to balance the expansion into a wider market with the need for increased commercial investment?
A: Christian Henry emphasized that Vega was designed for simplicity and ease of use, reducing the support burden. The company plans to leverage distributors and existing customer bases, such as Sequel II users, to manage commercial investment while expanding into new market segments.

For the complete transcript of the earnings call, please refer to the full earnings call transcript.